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KMID : 0377619750280040381
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Korean Jungang Medical Journal
1975 Volume.28 No. 4 p.381 ~ p.386
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Intra Uterine Contraceptive Devices and Carcinogenetic Effect
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Abstract
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As Meyer and Mishell stated, histologically evidence of chronic nonbacterial endometritis persists for long period in endometrial specimen obtained from IUD users. It is generally accepted that this reaction in the endometrial cavity is main causative factor for the contraceptive effect of the IUD.
Since the effect of all known carcinogenes in human is delayed, however, with a long patency period of about a decade, it will not be possible to make a definite statement on this point until substantial numbers of women have worn IUD´s for a long period.
At persent time, there is no evidence that IUD causes cancer in woman. Many long term studies have shown that there is no clinical evidence that the IUD causes an increased incidence of carcinoma of the endometrium and cervical carcinoma.
Causative factors of uterine carcinoma, causative factors for the contraceptive effects of IUD, histopathologic changes in uterine specimens obtained from IUD users and some other problems retated to the effect of IUD are also discussed.
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KEYWORD
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